Jurnal Kedokteran Meditek

Hubungan Kecacingan dan Status Gizi Balita Usia 2-5 Tahun di Beberapa Posyandu di Wilayah Kebon Jeruk, Kota Jakarta Barat

Monica Puspa Sari — 2026-03-26

Introduction: Soil-transmitted helminth (STH) infections are a global health problem, especially among young children in developing countries. These infections affect children's nutritional status through various mechanisms, such as impaired nutrient absorption and chronic blood loss. Purpose: This study aims to analyze the relationship between STH infection and the nutritional status of children aged 2–5 years at several integrated Posts in the Kebon Jeruk subdistrict of West Jakarta. Method: This study used an analytic descriptive design with a cross-sectional design. A total of 153 toddlers were selected through a total sampling technique from six health posts. Worm infestation status was determined through stool examination using the Kato-Katz method. Nutritional status was assessed using three anthropometric indicators: weight for age, height for age and weight for height based on the World Health Organization Child Growth Standards. Data analysis was performed using the Fisher test. Results: The prevalence of worm infection in toddlers was 5,2%. Ascaris lumbricoides was the most common cause, with mild infection rates. Based on nutritional status, most toddlers infected with STH had normal weight for age, normal height for age, and good nutritional weight for height. There was no significant relationship between STH infections and nutritional status (p>0.05). Conclusion: The prevalence of STH infections in toddlers in the study was quite low. There was no significant association between STH infections and nutritional status in toddlers. Continuous prevention and control interventions for worm infection, along with routine monitoring of nutritional status, are needed to ensure worm-free status.

Effect of Kawa Gambir (Uncaria gambir Roxb.) Leaves on Serum LDL in Diabetic Model Rats

Muhammad Abi Ghoffari Siregar — 2026-03-30

Background: Kawa gambir leaves, dried in a furnace and brewed as tea, are rich in flavonoids, phenolics, steroids, and tannins and have antioxidant, antihyperglycemic, and antidyslipidemic properties. In diabetes, elevated low-density lipoprotein (LDL) is a dyslipidemic abnormality that increases atherogenic risk. However, the effect of Kawa gambir on LDL in diabetic conditions remains unclear. Objective: To evaluate the effect of Kawa gambir leaf administration on LDL in alloxan-induced diabetic rats. Methods: This experimental study used a post-test-only control group design in 36 Wistar rats randomized into six groups: K−, K+, MET, P1, P2, and P3. Diabetes was induced with alloxan in K+, MET, and P1–P3. MET received metformin, whereas P1, P2, and P3 received Kawa gambir infusions at 1, 2, and 4 g/100 mL once daily for 4 weeks. Serum LDL was estimated using the Friedewald formula. Data were analyzed by one-way ANOVA followed by Least Significant Difference post hoc testing. Results: Mean±SD LDL levels (mg/dL) were 37.16±3.03, 59.90±8.91, 41.30±6.74, 40.60±5.75, 38.95±10.15, and 40.33±7.01 in K−, K+, MET, P1, P2, and P3, respectively. Group differences were significant (p=0.001). The largest numerical reduction versus K+ was found in P2, with a difference of 20.95 mg/dL (95% CI 8.64–33.26). Conclusion: Kawa gambir infusion significantly reduced LDL compared with the untreated diabetic control. Although the 2 g/100 mL group showed the lowest LDL numerically, no significant differences were observed among active treatment groups. These findings support Kawa gambir as an antidyslipidemic agent in diabetic dyslipidemia.

Hubungan Penggunaan Kontrasepsi Hormonal Dengan Kejadian Preeklampsia Di RSUP Persahabatan

Agung Junnata — 2026-03-20

Introduction: Preeclampsia is one of the leading causes of maternal morbidity and mortality in Indonesia. Several studies have reported that hormonal contraception may affect blood pressure and vascular function, thereby potentially contributing to the development of preeclampsia. However, the available evidence remains inconsistent. Purpose: This study aimed to determine the association between maternal age, parity, and history of contraceptive use, particularly hormonal contraception, and the occurrence of preeclampsia among pregnant women. Methods: This study employed an observational analytic design with a cross-sectional approach using secondary data from the medical records of pregnant women at RSUP Persahabatan Jakarta during May–July 2025. A total of 138 respondents were selected using a simple random sampling technique. Univariate analysis was conducted to describe subject characteristics, while bivariate analysis was performed using the Chi-square test or Fisher’s exact test, with a significance level of (p < 0.05.) Results: The prevalence of preeclampsia was 10.87%. There was a significant association between maternal age and the occurrence of preeclampsia (p < 0.001), as well as between parity and preeclampsia (p = 0.049). A history of contraceptive use was also significantly associated with preeclampsia (p = 0.014). However, no significant association was found between the type of contraception (hormonal vs non-hormonal) or the duration of hormonal contraceptive use and preeclampsia. Conclusion: Maternal age, parity, and history of contraceptive use were associated with preeclampsia. However, the type and duration of hormonal contraceptive use were not shown to increase the risk of preeclampsia in this study population.