Jurnal Kedokteran Meditek

Daftar Penulis dan Kata Kunci

Jurnal Kedokteran Meditek — 2025-01-30

Daftar Reviewer

Jurnal Kedokteran Meditek — 2025-01-30

Gambaran Pengetahuan Ablasio Retina pada Mahasiswa Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana

Santi Anugrahsari — 2025-01-27

Introduction: Retinal detachment is the visual nerve layer in the eyeball from the lower layer or retinal layer of pigment epithelium with accumulation in subretinal fluid. The clinical manifestation of retinal detachment is that the patient's vision can decrease from mild to severe. The symptom that suf erers often complain about is floaters, which are visible objects floating around. Purpose: The research is to determine the knowledge of retinal detachment among medical students at the Faculty of Medicine and Health Sciences, Krida Wacana Christian University. Methods: The design of this research is cross-sectional. Participants completed the questionnaire via Google form from 7 December 2022 to 15 December 2022. This research used random sampling; sample selection was carried out randomly. Participants numbered 108 students. Results: Students who had a high level of knowledge 69 respondents (63.9%), followed by a low level of knowledge, namely 22 respondents (20.4%), and then for a medium level of knowledge there were 17 respondents (15.7%). Conclusion: Most students at the Faculty of Medicine and Health Sciences, Krida Wacana Christian University have a high level of knowledge. This study had variations in respondents' knowledge levels because there were pre-clinical and clinical clerkship students

Pengaruh ekstrak ikan patin pada aktivitas katalase dan kadar MDA serum tikus yang diinduksi aloksan

Fitri Handajani — 2025-01-30

Introduction: Pangasius fish is known to contain antioxidants. Catalase is an enzymatic antioxidant whose role is to reduce oxidative stress. Oxidative stress results in fat oxidation which can be checked by Malondialdehyde (MDA) levels. Alloxan induction will cause oxidative stress. Purpose: This study aims to decide the role of Pangasius extract on catalase and MDA activity in alloxan-induced experimental animals. 24 hundred Rattus norvegicus were isolated into K0 the group without treatment, K1 was the group induced by an intraperitoneal (i.p) alloxan dose of 150 mg/kgBB on the 7th day, K2 was the group that was induced by an alloxan dose of 150 mg/kgBB i.p on the 7th day and given Pangasius fish oil extricate dosage of 73 mg/kgBB on the 10th day intragastric every day to 14 days. Results: The data investigation showed that there were significant differences in pancreatic catalase activity between groups K0 and K1 (p=0.001) and between groups K1 and K2 (p=0.001). These conditions indicate that Pangasius extract can scavenge free radicals so that there is no decrease in catalase activity in the pancreas. Pancreatic MDA levels showed significant results between groups K0 and K1 (p=0.010) and between groups K1 and K2 (p=0.010). This is due to the ability of the antioxidants contained in Pangasius fish extract to reduce free radicals thereby reducing oxidative stress resulting in decreased lipid peroxidation. Conclusion: the administration of Pangasius extract 73 mg/kgBW can decrease free radicals formed due to alloxan induction so that it can increase catalase activity and reduce pancreatic MDA

Perbedaan Rasio Trombosit Limfosit Pre dan Post Terapi Kemoradiasi Kanker Serviks di Rumah Sakit Pusat Angkatan Laut dr. Ramelan Surabaya

Purwo Diva Nadib Marbentan — 2025-01-27

Introduction: Cervical cancer is caused by persistent infection with HPV transmitted through sexual intercourse. Chemoradiation is often used in the treatment of cervical cancer because it can reduce recurrence and further cell growth and can increase survival. Increased Platelet Lymphocyte Ratio (RTL) can be used to track the progression of cervical cancer and the degree of differentiation of cancer cells. High RTL indicates a worse degree of cell differentiation and vice versa. Purpose: The aim of this study was to determine the difference in RTL in cervical cancer patients pre and post chemoradiation therapy. Methods: The research design is cross-sectional with total sampling. Data was taken from medical records of cervical cancer patients at the Department of Obstetrics and Gynaecology, RSPAL dr. Ramelan Surabaya in year 2000 - 2023. Results: The average RTL for cervical cancer patients before chemoradiation was 193.1293; and after chemoradiation 169.5459. The results of the Wilcoxon signed rank test showed a significant decrease (p < 0.001). This research proves that there is a significant difference in the Platelet Lymphocyte Ratio (RTL) of stage ≥ IIB cervical cancer patients pre- and post-chemoradiation therapy. Statistical tests show significant results. Conclusion: Chemoradiation has been proven to significantly reduce RTL, and it can be concluded that giving chemoradiation to cervical cancer stage IIIB and above provides good results.

Comparison of Depression Levels in Early and End Preclinical Students at Pelita Harapan University

Claresta Janice Budianto — 2025-01-27

Introduction: Mental health is a crucial concern globally and in Indonesia, especially among medical students who face higher rates of depression than the general population due to academic pressure, high expectations, and social stress. Depression can negatively affect academic performance and future careers. Studies show varying results regarding depression levels between early and end preclinical students. Purpose: This study aims to compare the level of depression in early to end preclinical students at Pelita Harapan University and to see whether there is a relationship between gender and social support and the level of depression. Methods: This cross-sectional study was conducted among 333 preclinical students from the Faculty of Medicine, Pelita Harapan University, in January-March 2024. The data was collected using the Beck Depression Inventory-II and the Multidimensional Scale of Perceived Social Support Questionnaire. Data analysis was performed using SPSS version 26 (chi-square statistical test). Results: The study found no statistically significant difference in depression levels between early and end preclinical students (p-value 0.348). There is a relationship between social support and the level of depression in preclinical students of the UPH Medical Faculty, with a (p-value of 0.001). However, no significant relationship was found between gender and the level of depression in preclinical students, with a p-value of 0.093. Conclusion: Conducted outside major metropolitan areas like Jakarta, the study offers insights into how depression manifests in different geographic and socio-economic contexts. The findings can be used as a consideration for making a faculty or university policy to improve mental health management for medical students, ensuring an effective learning process.

Self Stretching Exercise Lebih Efektif Dibandingkan Mckenzie Exercise Dalam Mengurangi Keluhan Low Back Pain Non-Spesifik

Gracia Silvany Yustina Mandowen — 2025-01-27

Introduction: The activities of garment workers who work with repetitive movements over a long time can influence the emergence of musculoskeletal complaints, one of which is low back pain, which is non-specific. Low back pain non-specific complaints impact functional activities and affect workers' work. Purpose: This study aims to determine the effect of the stretching exercise and McKenzie exercise in reducing pain and increasing functional activity in garment workers with non-specific low back pain. Methods: This type of research is experimental with a pre-test and post-test control group design. Treatment is given in 12 sessions over 4 weeks and carried out from April to May 2024. The research subjects were garment workers who met the inclusion and exclusion criteria with 22 people, divided into group I (n = 11 people) given the stretching exercise and group II (n = 11 people) given the McKenzie exercise. Results: The results of the difference test between groups I and II used the Mann-Whitney U test on the Visual Analog Scale (p < 0.05) and Oswestry Disability Index values (p < 0.05). Methods: It was concluded that self-stretching exercise was more effective than McKenzie exercise in reducing pain and increasing functional activity in garment workers with non-specific lower back pain

Correlation of Uric Acid Levels with Lipid Profile among MCU Patients

Aghnia Hidayah — 2025-01-27

Introduction: Uric acid (C5H4N4O3) is a product of purine degradation and can act as a pro-oxidant substance because of the formation of ROS through the enzymatic activity of xanthine oxidase. Previous research has shown that uric acid can affect lipid metabolism in the body. Purpose: This study aims to explore the relationship between lipid profiles in MCU patients and uric acid levels. This study employs a cross-sectional design, and we will analyze the data using linear regression. Methods: This study is an observational analytic study without intervention, using a cross-sectional study design. The research data came from secondary data, especially the medical records of MCU patients. Researchers selected the study sample using a random sampling technique. The study uses 86 secondary data samples. Results: Linear regression analysis reveals a significant positive correlation between uric acid and triglycerides (p-value < 0.001 and r = 0.464), total cholesterol (p-value = 0.018 and r = 0.255), and LDL (p-value = 0.011 and r = 0.273). A significant negative correlation exists between uric acid levels and HDL (p-value < 0.001 and r = 0.477). Increased uric acid levels are associated with higher levels of TG, TC, and LDL, as well as a decrease in HDL levels. The average levels of LDL and total cholesterol are 140.27 mg/dl and 206.66 mg/dl, respectively, which are at the high threshold, while all other variables are within normal limits. Conclusion: This study concludes that uric acid levels and lipid profile levels are significantly related

Meckel's Diverticulum-Induced Intussusception Coinciding with Diabetes Mellitus in a Young Adult Male

Reza Aditya Digambiro — 2025-01-27

Introduction: Intussusception in adults, especially when caused by Meckel's Diverticulum, is a rare occurrence, often presenting with nonspecific symptoms such as abdominal pain and nausea, making it challenging to diagnose. When concurrent with conditions like diabetes mellitus, the situation need particular care. Case Illustration: A 27-year-old male with a medical history of diabetes presented with severe right abdominal pain, nausea, and a reduced appetite. Initial symptomatic treatment did not alleviate the condition. Subsequent CT scans revealed an ileo-ileal intussusception triggered by Meckel's Diverticulum and partial high obstruction ileus, leading to surgical intervention. Discussion: Ileo-ileal resection (end to end anastomosis) and adhesiolysis surgery were successfully performed, followed by vigilant postoperative monitoring for complications, effective pain management, maintenance of drain patency, and careful glucose level monitoring. The patient's significant postoperative improvement underscores the importance of early diagnosis and timely surgical intervention in managing Meckel's Diverticulum-induced intussusception in adults. Conclusion: The clinical course also highlighted the importance of tailoring postoperative care considering the patient's comorbidities, in this case, diabetes mellitus. This case served as a reminder for clinicians to consider Meckel's Diverticulum as a potential cause of intussusception in adults presenting with abdominal pain.