Efektivitas Tanaman Sambiloto (Andrographis Paniculata) dan Senyawa Andrographolide dalam Menghambat Infeksi COVID-19 : Literature Review

Shintia Christina; Kristin Natalia  Meta Kali; Reni Angeline

doi:10.36452/jmedscie.v1i1.2496

Authors

Shintia Christina Departemen Ilmu Patologi Anatomi, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta, Indonesia.
Kristin Natalia Meta Kali Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta
Reni Angeline Departemen Ilmu Patologi Anatomi, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana, Jakarta, Indonesia.

DOI:

https://doi.org/10.36452/jmedscie.v1i1.2496

Keywords:

Andrographolide, antiviral, COVID-19, Andrographis paniculata

Abstract

Sambiloto (Andrographis paniculata) has long been used as a herbal medicine by local Indonesian people, especially because it is easy to find in the yard of the house. Since the onset of the COVID-19 pandemic, various handling efforts have been carried out, ranging from pharmacological and non-pharmacological. Various herbal plants that have the potential to be used as COVID-19 treatments have begun to be tested, including A. paniculata. To find out the benefits and mechanisms of A. paniculata in the treatment of COVID-19, a literature review study was conducted by tracing data in the form of scientific journals published in the last 2 years since the pandemic began. At the end of the results of this study, A. paniculata demonstrated its function in inhibiting COVID-19 through the mechanism of preventing virus attachment to surface receptors and inhibiting viral replication.