Comparison of the Contamination Rate between Lowenstein-Jensen Media and BACTEC MGIT 960 as a Culture Method for Mycobacterium tuberculosis

  • Athira Presialia Faculty of Medicine, University of Indonesia
  • Ariyani Kiranasari Department of Clinical Microbiology, Faculty of Medicine, University of Indonesia
Keywords: BACTEC MGIT 960, contamination rate, Lowenstein-Jensen, Mycobacterium tuberculosis


Culture is remaining a gold standard for tuberculosis diagnostic test. Lowenstein-Jensen and BACTEC MGIT 960 are two mediums that are recently used, however, contamination by other bacteria or fungal may interfere with the result’s interpretation. This study aims to find out the contamination rate comparison between Lowenstein-Jensen media and BACTEC MGIT 960. This is a cross-sectional study with 204 samples from the Clinical Microbiology Laboratory of FKUI-RSCM which meets the research criteria. Data were analyzed using McNemar test for paired proportion data. Out of the 204 subjects, the majority are male (62,8%) between the age group of 26-35 years (34,3%). Based on McNemar test, there is no significant difference of contamination rate between LJ media and BACTEC MGIT 960 (p=1.000). A significant difference in the proportion of positive culture result between samples cultivated with LJ media and BACTEC MGIT 960 was not shown either (p=1.000). In conclusion, there is no significant difference in contamination rate between LJ media and BACTEC MGIT 960.


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How to Cite
Presialia, A., & Kiranasari, A. (2020). Comparison of the Contamination Rate between Lowenstein-Jensen Media and BACTEC MGIT 960 as a Culture Method for Mycobacterium tuberculosis. Jurnal Kedokteran Meditek, 26(2), 36-42.
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