Diabetes Melitus Sebagai Faktor Risiko Tuberkulosis

Ida Bagus Aditya Nugraha; Wira Gotera; Wayan Evie Frida  Yustin

doi:10.36452/jkdoktmeditek.v27i3.2126

Authors

Ida Bagus Aditya Nugraha Program Studi Pendidikan Dokter Spesialis Pulmonologi dan Ilmu Kedokteran Respirasi FK Udayana-RSUP Sanglah, Denpasar, Indonesia
Wira Gotera Divisi Endokrinologi/ Penyakit Dalam FK Udayana-RSUP Sanglah, Denpasar, Indonesia
Wayan Evie Frida Yustin Program Studi Pendidikan Dokter Spesialis Pulmonologi dan Ilmu Kedokteran Respirasi FK Udayana-RSUP Sanglah, Denpasar, Indonesia

DOI:

https://doi.org/10.36452/jkdoktmeditek.v27i3.2126

Keywords:

diabetes melitus, faktor resiko, tuberkulosis

Abstract

Diabetes melitus (DM) tidak hanya meningkatkan risiko tuberkulosis (TB) aktif tetapi juga memengaruhi hasil pengobatan. Beban penyakit TB, terutama di negara berkembang, tetap tinggi meskipun telah dilakukan berbagai upaya pencegahan. Diabetes melitus yang menyebabkan imunosupresi semakin diakui sebagai faktor risiko independen untuk TB. Diabetes melitus meningkatkan risiko berkembangnya TB dua hingga tiga kali lipat dan juga meningkatkan risiko kegagalan pengobatan TB, kekambuhan, dan kematian. Diabetes juga dapat menyebabkan penyakit parah, reaktivasi fokus TB yang tidak aktif, dan hasil pengobatan TB yang buruk. Beberapa obat antituberkulosis yang biasa digunakan secara terpisah dapat menyebabkan gangguan toleransi glukosa. Skrining tuberkulosis pada penderita diabetes dan skrining diabetes pada pasien tuberkulosis telah direkomendasikan. Hal ini perlu diterapkan mengingat efektivitas dan manfaatnya.

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