Laporan Kasus : Pseudotrombositopenia pada Pasien Pre-Operasi

Gregorio Gavriel  Singgih; Jullyanny Waty  Wijaya; Monica  Adisuhanto

doi:10.36452/jkdoktmeditek.v29i1.2550

Authors

Gregorio Gavriel Singgih Departemen Patologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Atmajaya, Jakarta, Indonesia
Jullyanny Waty Wijaya Departemen Patologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Atmajaya, Jakarta, Indonesia
Monica Adisuhanto Departemen Patologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Atmajaya, Jakarta, Indonesia

DOI:

https://doi.org/10.36452/jkdoktmeditek.v29i1.2550

Keywords:

EDTA, hitung trombosit, trombositopenia

Abstract

Pseudotrombositopenia didefinisikan sebagai jumlah hitung trombosit rendah palsu yang terukur oleh faktor alat analisis hematologi. Diketahui EDTA-dependent pseudotrombositopenia merupakan salah satu penyebab trombositopenia dengan prevalensi 0,1-2%. Pseudotrombositopenia yang tidak terdiagnosis dapat menyebabkan kesalahan dalam keputusan klinis. Laporan kasus ini disusun agar dapat meningkatkan kewaspadaan dalam mendiagnosis pseudotrombositopenia. Laki-laki 56 tahun melakukan pemeriksaan pre-operasi dan didapatkan adanya trombositopenia dengan jumlah trombosit 16.000/uL tanpa ditemukan adanya kelainan pada parameter koagulasi lainnya dan tidak terdapat adanya perdarahan aktif, Pada pemeriksaan morfologi darah ditemukan banyak platelet clumping. Dokter menduga adanya EDTA-dependent pseudotrombositopenia lalu melakukan pengambilan sampel darah kembali satu hari kemudian dengan menggunakan antikoagulan natrium sitrat. Sampel darah tersebut diperiksa dengan mesin hematologi Sysmex XN-550 dan didapatkan jumlah trombosit yaitu 112.000/uL. Bila dijumpai kondisi jumlah trombosit rendah / trombositopenia tanpa ada tanda klinis pendarahan yang jelas, maka perlu dipertimbangkan adanya EDTA-dependent pseudothrombocytopenia. Pemeriksaan morfologi darah tepi dan pengulangan darah lengkap menggunakan sampel darah dengan antikoagulan lainnya, yaitu natrium sitrat menjadi salah satu metode dalam menegakkan adanya EDTA-dependent pseudothrombocytopenia.

Author Biography

Jullyanny Waty Wijaya, Departemen Patologi Klinik, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Atmajaya, Jakarta, Indonesia

dr. Jullyanny is graduated as General Practitioner from Atma Jaya Catholic University in 2019. She finished Clinical Pathology Residency in 2015 at Brawijaya University Malang. She has 5+ years of experience in clinical laboratory science and management. She is also a teaching staff at Clinical Pathology Department, School of Medicine and Health Science, Atma Jaya Catholic University Indonesia. Other than teaching medical school students, she enjoys her life with her family.

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