Diagnosis dan Penatalaksanaan Paripurna Sindrom Sjögren

Authors

  • Riris Asti Respati Departemen Dermatologi dan Venereologi Fakultas Kedokteran Universitas Indonesia (FK UI)/RSPN dr. Cipto Mangunkusumo, Jakarta, Indonesia
  • Windy Keumala Budianti Departemen Dermatologi dan Venereologi Fakultas Kedokteran Universitas Indonesia (FK UI)/RSPN dr. Cipto Mangunkusumo, Jakarta, Indonesia

DOI:

https://doi.org/10.36452/jkdoktmeditek.v27i2.2034

Keywords:

manifestasi kulit, sindrom sika, sindrom sjögren, tata laksana

Abstract

Sindrom Sjögren (SS) adalah penyakit autoimun yang ditandai dengan infiltrasi limfosit pada kelenjar eksokrin dan menyebabkan sindrom sika. Patogenesis SS masih belum diketahui sepenuhnya namun diduga terdapat kerusakan epitel kelenjar eksokrin karena peningkatan respons sel B dan sel T terhadap autoantigen Ro (SS-A) dan La (SS-B). Manifestasi klinis SS dibedakan menjadi glandular dan ekstraglandular. Tatalaksana SS terdiri atas lokal dan sistemik yang bertujuan untuk meningkatkan kualitas hidup dengan mengurangi gejala kekeringan. Tinjauan Pustaka dibuat berdasarkan rangkuman dari berbagai artikel asli, baik laporan hasil penelitian atau sumber kepustakaan lain contohnya buku teks, jurnal, dan lain-lain. Tujuan tinjauan pustaka ini adalah untuk memberikan pengetahuan tata laksana terkini pada SS.

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Published

2021-06-25 — Updated on 2021-06-25

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How to Cite

Respati, R. A., & Budianti, W. K. (2021). Diagnosis dan Penatalaksanaan Paripurna Sindrom Sjögren. Jurnal Kedokteran Meditek, 27(2), 147–156. https://doi.org/10.36452/jkdoktmeditek.v27i2.2034

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Tinjauan Pustaka